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. 2026 Feb 9;14(3):e02151-25. doi: 10.1128/spectrum.02151-25

Fig 1.

Immune cell infiltration analysis in stomach adenocarcinoma. Heatmaps show NMF clustering and correlations between cell types. Boxplots reveal infiltration differences across groups. Survival curves demonstrate prognostic impact of specific immune cells.

Immune landscape profiling within the TME of STAD. (a) Heatmap of ICI clustering using NMF. (b) Boxplots showing differences in immune cell scores among INC groups; P-values were calculated using the Wilcoxon test. ns indicates no significant difference, * indicates P < 0.05, ** indicates P < 0.01, *** indicates P < 0.001 and **** indicates P < 0.0001. (c) Correlation heatmap of 24 immune cell types. (d) Bar plot of clinical stage distribution across INC groups. (e) Boxplots showing differences in infiltration levels of 24 immune cell types among INC groups. (f–i) Kaplan–Meier survival curves for CD4_T, MAIT, NK, and nTreg.