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. 2026 Feb 18;17:1763837. doi: 10.3389/fphys.2026.1763837

FIGURE 3.

Panel a presents an intersection bar plot visualizing gene set overlaps across six experimental groups, detailing intersection sizes and set sizes; panels b and c display biological process network diagrams with colored nodes and labels representing enriched pathways; panels d and e show circular protein-protein interaction networks for two distinct gene clusters, with central hub genes in larger, colored nodes.

Gene counts, functional analysis, and hub genes associated with Pattern 1 and Pattern 2. (a) UpsetR plot of all the gene sets of interest and their intersection sets. (b) Enrichment analysis of the intersection genes between DM and C9 (Pattern 1). (c) Enrichment analysis of the intersecting genes between BL and C8 (Pattern 2). (d) Concentric circle plot of genes in Pattern 1. Circle size and color, as well as label size, are positively correlated with gene degree. (e) Concentric circle plot of the top 100 genes in Pattern 2. Circle size and color, as well as label size, are positively correlated with gene degree. Note: DM, darkmagenta module; DO, darkorange module; BL, blue module; C4, Cluster 4; C8, Cluster 8; C9, Cluster 9.