Table 2.

Potential Risk Factors for Bleeding and All-Cause Death

	Any Bleeding		Procedure-Related Bleeding		Nonprocedure-Related Bleeding		All-Cause Death
	HR (95%CI)	P Value	HR (95%CI)	P Value	HR (95%CI)	P Value	HR (95%CI)	P Value
Endogenous noncardiac stratuma	0.88 (0.59-1.30)	0.51	0.83 (0.52-1.27)	0.40	1.64 (0.87-2.95)	0.12	1.06 (0.88-1.26)	0.54
Exogenous stratuma	0.65 (0.38-1.09)	0.086	0.75 (0.42-1.26)	0.29	0.33 (0.05-1.09)	0.72	0.98 (0.79-1.21)	0.86
IABP use	1.72 (1.27-2.31)	<0.001	1.68 (1.21-2.36)	0.002	2.80 (1.60-5.14)	<0.001	0.55 (0.47-0.63)	<0.001
Age ≥75 y	1.56 (1.13-2.14)	0.010	1.58 (1.08-2.24)	0.018	1.58 (0.87-2.68)	0.12	1.22 (1.01-1.45)	0.036
eGFR <60 mL/min/1.73 m2	0.79 (0.62-1.01)	0.067	0.75 (0.57-0.99)	0.042	0.95 (0.62-1.50)	0.82	1.43 (1.24-1.66)	<0.001
Hemoglobin <11 g/dL	0.94 (0.71-1.23)	0.63	0.99 (0.72-1.34)	0.94	0.72 (0.43-1.16)	0.18	1.13 (0.98-1.30)	0.089
Platelet <10 × 104/μL	1.25 (0.95-1.64)	0.12	1.19 (0.86-1.61)	0.28	1.64 (1.04-2.53)	0.035	1.22 (1.05-1.41)	0.009
D-dimer ≥5 mg/dL	1.30 (0.97-1.73)	0.074	1.18 (0.87-1.65)	0.29	1.84 (1.08-3.35)	0.024	1.19 (1.02-1.38)	0.028
CRP ≥5 mg/dL	0.77 (0.41-1.46)	0.41	0.79 (0.36-1.51)	0.51	0.68 (0.17-1.85)	0.50	1.04 (0.79-1.34)	0.79
Lactate >5 mmol/L	1.47 (0.69-1.64)	0.29	1.43 (0.68-3.67)	0.37	1.40 (0.43-8.56)	0.63	1.39 (1.01-1.97)	0.044
Antithrombotic agents	0.86 (0.61-1.22)	0.39	0.86 (0.57-1.25)	0.43	1.04 (0.57-1.77)	0.90	0.79 (0.65-0.94)	0.010
Catheter laboratory puncture	1.26 (0.99-1.61)	0.064	1.14 (0.86-1.65)	0.37	1.27 (0.83-1.94)	0.27	0.96 (0.84-1.10)	0.59
Institute Q2b	1.04 (0.79-1.36)	0.80	1.00 (0.73-1.35)	0.99	1.23 (0.75-1.97)	0.40	1.02 (0.88-1.18)	0.79
Institute Q3b	1.15 (0.79-1.67)	0.46	1.11 (0.71-1.67)	0.65	1.79 (0.96-3.16)	0.066	1.16 (0.95-1.42)	0.15
Institute Q4b	1.67 (1.11-2.52)	0.020	1.44 (0.86-2.30)	0.16	2.36 (1.18-4.37)	0.018	1.10 (0.83-1.42)	0.50

Abbreviations as in Table 1.

^aRisks relative to the endogenous cardiac stratum.

^bRisks relative to the reference category (Institute Q1).