Fig. 2.
Multi-variate logistic regression comparing the serum methotrexate concentration at 4 h post-infusion and the occurrence of any acute kidney injury for adult patients with lymphoma receiving a high dose. The solid blue line represents the plotted probability for patients on a ≤ 3.5-g/m2 dose of high-dose methotrexate. The solid black line represents the plotted probability for patients on an 8-g/m2 dose of high-dose methotrexate. The shaded regions represent the 95% confidence interval. The points represent patient data. The dashed black lines represent the 50% probability for any acute kidney injury for each protocol dose and are provided for visual reference only