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. 2026 Feb 13;49(Suppl 2):e20250179. doi: 10.1590/1678-4685-GMB-2025-0179

Table 2- . Comparative summary of early 20th-century quarrel between Mendelism and Darwinism.

Aspect Mendelism (Early 20th Century) Darwinism (Early 20th Century)
View of Variation Discontinuous variation; traits inherited as discrete units (genes) Continuous variation; small, incremental changes
Mechanism of Inheritance Clear, gene-based segregation and dominance (Mendel’s laws) Lacked a precise mechanism; often relied on blended inheritance or pangenesis
Mechanism of Evolutionary Change Emphasis on mutations (sometimes large/sudden, as in de Vries’ saltationism) Gradual accumulation of small variations through natural selection
Strengths Provided a robust model for inheritance; explained how traits are transmitted Provided a powerful mechanism for adaptation and the shaping of populations over time
Weaknesses Lacked an explanation for adaptation in natural populations Lacked a workable theory of heredity
Philosophical Orientation Mechanistic, gene-centered, often experimental Naturalistic, population-level, often statistical and observational
Main Proponents William Bateson, Hugo de Vries, Carl Correns, Erich von Tschermak W. F. R. Weldon, Karl Pearson, traditional Darwinists
Criticism of the Other View Saw Darwinism as vague, outdated, and lacking genetic basis Viewed Mendelism as too simplistic, based on limited lab traits, and disconnected from natural populations