Table 4.
Adverse events observed according to assigned antibiotic (intention to treat populations). Figures are numbers (percentage) of patients
| Pristinamycin(n=139) | Penicillin(n=150) | |
|---|---|---|
| Patients with ⩾1 event | 75 (54) | 83 (55) |
| Patients with at least one possible event related to drug* | 39 (28) | 26 (17) |
| Patients withdrawn prematurely | 15 (11) | 25 (17) |
| Event related to drug related in ⩾2 patients: | ||
| Abdominal pain | 2 | 2 |
| Gastrointestinal disorder | 2 | 0 |
| Dyspepsia | 3 | 0 |
| Nausea | 4 | 0 |
| Vomiting | 7 | 0 |
| Diarrhoea | 14 | 4 |
| Liver function test abnormality | 4 | 6 |
| Allergic reaction | 0 | 2 |
| Rash | 4 | 4 |
| Sweats | 2 | 0 |
| Moniliasis | 1 | 1 |
| Urticaria | 1 | 1 |
*
As stated by investigator.