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EP300 supports proliferation and clonogenicity. (A–B) CCK-8 assays show decreased viability from 48 to 72 h after EP300 knockdown in SK-hep-1 and Huh-7 (**p≤0.01); (C–D) representative colony plates illustrate fewer colonies; (E–F) quantification confirms marked reductions (***p < 0.0001). Experiments were performed in ≥ 3 replicates
