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In vivo EP300 knockdown suppresses tumor growth. (A) representative mice bearing SK-hep-1 or Huh-7 xenografts; (B) tumor volumes increase more slowly after si-EP300-4; (C) body weight is comparable between groups; (D–E) endpoint tumors are smaller with significantly lower weights in si-EP300 cohorts (***p < 0.0001). Curves/bars represent mean±SEM
