. 2026 Feb 4;26:510. doi: 10.1186/s12879-026-12531-3

Table 2.

Diagnostic performance of the Bioline™ HIV/Syphilis duo RDT and determine HIV1/2

HIV1/2 RDTs	Sensitivity 95% CI	Specificity 95% CI	PPV 95% CI	NPV 95% CI	Accuracy 95% CI	Kappa 95% CI
Determine	100% (95% CI: 98.8–100)	97.10% (95% CI: 93.8–98.7)	98.2% (95% CI: 96.1–99.2)	100% (95% CI: 98.1–100)	99% (95% CI: 97–100)	98% (95% CI: 96.7–99.9)
Bioline HIV	99.70% (95% CI: 98.30–99.9)	98.5% (95% CI: 95.58–99.5)	99.1% (95% CI: 97.40–99.7)	99.5% (95% CI: 97.3–99.9)	99.1% (95% CI: 97-99.7)	98% (95% CI: 96.7–99.9)

HIV1/2 RDTs

Sensitivity
95% CI

Specificity
95% CI

PPV
95% CI

NPV
95% CI

Accuracy
95% CI

Kappa
95% CI

Determine

100%

(95% CI: 98.8–100)

97.10%

(95% CI: 93.8–98.7)

98.2%

(95% CI: 96.1–99.2)

100%

(95% CI: 98.1–100)

99%

(95% CI: 97–100)

98%

(95% CI: 96.7–99.9)

Bioline HIV

99.70%

(95% CI: 98.30–99.9)

98.5%

(95% CI: 95.58–99.5)

99.1%

(95% CI: 97.40–99.7)

99.5%

(95% CI: 97.3–99.9)

99.1%

(95% CI: 97-99.7)

98%

(95% CI: 96.7–99.9)

Legend: PPV: positive predictive value, NPV: negative predictive value, CI: Confidence Interval