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. 2026 Feb 4;26:207. doi: 10.1186/s12872-026-05571-9

Table 2.

Sensitivity analysis comparing Meta-Analysis with and without Pereira et al. [15]

Outcome All Four Studies Excluding Pereira et al. Interpretation
Stroke/Reversible Ischemic Neurological Deficit RR 0.80 (0.06–11.50), P = 0.87 RR 0.80 (0.06–11.50), P = 0.87 No change
Systemic Embolism RR 0.27 (0.01–6.11), P = 0.41 RR 0.27 (0.01–6.11), P = 0.41 No change
Major Bleeding RR 0.55 (0.11–2.64), P = 0.46, I² = 0% RR 0.81 (0.12–5.34), P = 0.82, I² = 4% Direction and significance unchanged
Any Bleeding RR 1.01 (0.31–3.30), P = 0.99, I² = 36% RR 1.72 (0.43–6.91), P = 0.44, I² = 16% Trend toward more DOAC bleeding in subset; overall conclusion stable