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. 2026 Mar 14;32(10):115167. doi: 10.3748/wjg.v32.i10.115167

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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

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Incidence of hypervasopressinemia after liver resection according to surgical extent. The major liver resection (MajLR) group (orange bars) had a higher proportion of patients with plasma arginine vasopressin ≥ 4.0 pg/mL compared to the minor liver resection group (green bars). Hypervasopressinemia was significantly more frequent in the MajLR group on postoperative day (POD) 1 and 5. Although the early increase on POD 1 likely reflects intraoperative fluid-restrictive management and hemodynamic shifts inherent to major liver resection, the persistence to POD 5 despite postoperative rehydration suggests a prolonged neuroendocrine response proportional to surgical stress. ^aP < 0.05. MinLR: Minor liver resection; MajLR: Major liver resection; LR: Liver resection; POD: Postoperative day.