Table 3.
Comparison of perioperative variables between patients undergoing minor and major liver resection, n (%)
|
|
MinLR group (n = 45)
|
MajLR group (n = 11)
|
P value
|
| Age (years), median (IQR) | 69 (65-75) | 69 (64-77) | 0.942 |
| Sex (men/women) | 31 (68.9)/14 (31.1) | 6 (54.6)/5 (45.5) | 0.368 |
| Indication of liver resection | 0.053 | ||
| Colorectal liver metastasis | 23 (51.1) | 2 (18.2) | |
| Hepatocellular carcinoma | 15 (33.3) | 5 (45.5) | |
| Biliary tract cancer | 2 (4.4) | 3 (27.3) | |
| Others | 5 (11.1) | 1 (9.1) | |
| Indocyanine green retention rate at 15 minutes (%), median (IQR) | 10.0 (7.4-17.2) | 10.4 (6.2-14.1) | 0.458 |
| Kinetic indocyanine green elimination rate constant, median (IQR) | 0.155 (0.118-0.173) | 0.165 (0.131-0.186) | 0.265 |
| Number of complete resected Couinaud segments, median (IQR) | 0 (0-1) | 3 (3-4) | < 0.001b |
| Laparoscopic surgery | 19 (42.2) | 3 (27.3) | 0.363 |
| Extrahepatic bile duct resection | 0 (0.0) | 4 (36.4) | < 0.001b |
| Concomitant colorectal resection | 3 (6.7) | 0 (0.0) | 0.379 |
| Operative duration (minute), median (IQR) | 278 (207-337) | 382 (301-665) | 0.002b |
| Intraoperative blood loss (mL), median (IQR) | 290 (67-484) | 1124 (150-2188) | 0.015a |
| Intraoperative red blood cell transfusion | 7 (15.6) | 4 (36.4) | 0.119 |
| Intraoperative fluid balance (mL/kg/hour), median (IQR) | 8.9 (6.8-12.5) | 6.9 (4.5-8.8) | 0.058 |
| Preoperative body weight (kg), median (IQR) | 58.1 (52.2-68.0) | 59.7 (54.0-65.0) | 0.845 |
| Maximum postoperative weight gain (%), median (IQR) | 2.6 (1.2-6.3) | 3.5 (1.0-6.4) | 0.918 |
| Complications (Clavien-Dindo grade ≥ IIIa) (%) | 6 (13.3) | 6 (54.6) | 0.003b |
a
P < 0.05.
b
P < 0.01.
Statistical analyses: Mann-Whitney U test for continuous variables, χ² or Fisher’s exact test for categorical variables. Minor liver resection < 3 Couinaud segments, major liver resection ≥ 3 Couinaud segments (Brisbane 2000 classification). MinLR: Minor liver resection; MajLR: Major liver resection; IQR: Interquartile range.