Skip to main content
. 2002 Oct 1;99(21):13516–13521. doi: 10.1073/pnas.192283399

Figure 1.

Figure 1

Location of F1395 in nNOS. (Upper) Stacking interaction between phenyl of F1395 (green) and FAD isoalloxazine ring (blue) in a crystallized FNR fragment of nNOS (12). Left and Right of Upper are zoom out and 300% zooming picture of the FNR module of nNOS, respectively. (Lower) C-terminal sequence alignments for rat neuronal NOS (nNOS, SWISS-PROT accession no. P29476), mouse inducible NOS (iNOS, accession no. P29477), bovine endothelial NOS (eNOS, accession no. P29473), rat cytochrome P450 reductase (CYPR, accession no. P00388), spinach ferredoxin:NADP+ reductase (FNR, accession no. P00455), Escherichia coli. sulfite reductase flavoprotein α-component (SIR-FP, accession no. P38038), and Caenorhabditis elegans methionine synthase reductase (MSR, accession no. Q17574). The conserved aromatic residue is marked by red.