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. 2005 Dec 1;115(12):3634–3640. doi: 10.1172/JCI23626

Figure 6.

Figure 6

Transplantation of wild-type bone marrow to PUMA-G–deficient recipients restores the flushing response to NA. (A) RT-PCR of cDNAs from BM or MHC class II–positive cells from the outer ear of PUMA-G–deficient mice transplanted with wild-type BM or PUMA-G–deficient bone marrow using PUMA-G– or GAPDH-specific primers. (B) Original LDF recordings of the flushing response induced by 200 mg/kg NA injected i.p. at the time points indicated by arrows. The experiments were performed 20 weeks after transplantation of PUMA-G+/+ (lower panel) or PUMA-G–/– (upper panel) BM to PUMA-G–/– recipients. (C) Statistical evaluation of NA effects on LDF in PUMA-G–/– mice transplanted with wild-type (n = 8) or PUMA-G–/– bone marrow (n = 5). *P < 0.05 vs. animals transplanted with PUMA-G–/– bone marrow.