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Central control by GLP-1 of muscle GSK3β phosphorylation. Muscle content in 46-kDa GSK3β-P in C57BL/6 mice with ACF or Ex9 infused into their brains, GLP-1 receptor KO mice, and MIRKO mice infused with ACF or Ex9 into their brains during a 20-mM hyperglycemic hyperinsulinemic clamp. The mean of 4 mice per group is shown. *P < 0.05 versus ACF-infused WT mice.
