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Central control by central GLP-1 of ChREBP and HKII mRNA in muscles. (A) ChREBP and (B) HKII mRNA concentrations (AU) were assessed in muscles of C57BL/6 and MIRKO mice during hyperinsulinemic euglycemic (5.5 mM, G5) or hyperglycemic (20 mM, G20) clamps. Some hyperglycemic C57BL/6 and MIRKO mice had Ex9 simultaneously infused into their brains. The mean of 4 mice per group is shown. *P < 0.05 versus euglycemic WT mice.
