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. 2026 Feb 12;18(2):67. doi: 10.21037/jtd-2025-aw-1868

Table 2. Logistic analysis of clinical features.

Characteristics Univariable logistic regression Multivariable logistic regression
OR (95% CI) P value OR (95% CI) P value
Gender 0.178 (0.109–0.292) <0.001 0.317 (0.159–0.634) 0.006
Age 0.984 (0.979–0.988) <0.001 0.998 (0.967–1.031) 0.93
CEA 1.056 (0.614–1.813) 0.87
CA125 0.500 (0.120–2.077) 0.42
Diameter 0.646 (0.557–0.748) <0.001 1.085 (0.642–1.833) 0.80
Lobulation sign 0.481 (0.353–0.657) <0.001 4.068 (1.376–12.037) 0.03
Bubble sign 0.329 (0.221–0.488) <0.001 0.688 (0.346–1.368) 0.37
Spiculation 0.367 (0.233–0.578) <0.001 0.831 (0.393–1.758) 0.68
Pleural indentation 0.537 (0.347–0.829) 0.02 1.907 (0.863–4.212) 0.18
Cystic lung cancer 0.143 (0.025–0.829) 0.07
Peripheral GGO 0.162 (0.079–0.335) <0.001 0.719 (0.279–1.852) 0.57
Bronchus Sign 0.250 (0.147–0.425) <0.001 0.587 (0.284–1.213) 0.23
Vacuolation 0.291 (0.182–0.464) <0.001 0.759 (0.372–1.548) 0.52
Margin 0.344 (0.257–0.460) <0.001 1.022 (0.113–9.253) 0.99
Density 0.491 (0.412–0.584) <0.001 7.593 (2.226–25.894) 0.007

CA125, cancer antigen 125; CEA, carcinoembryonic antigen; CI, confidence interval; GGO, ground-glass opacity; OR, odds ratio.