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. 2026 Feb 26;18(2):70. doi: 10.21037/jtd-2025-aw-2045

Table 2. Surgical and anesthetic details.

Variables Missing AKI (n=318) Non-AKI (n=1,011) P value
Operative approach 3 (0.2) 0.003†
   Open thoracotomy 190 (59.7) 507 (50.1)
   VATS 128 (30.3) 504 (49.9)
Types of operation 3 (0.2) 0.27†
   Wedge resection 47 (14.8) 169 (16.7)
   Segmentectomy 7 (2.2) 43 (4.3)
   Lobectomy 124 (39.0) 344 (34.1)
   Pneumonectomy 6 (1.9) 15 (1.5)
   Decortication 89 (28.0) 269 (26.6)
   Other procedures 45 (14.1) 110 (16.8)
Side of operation 3 (0.2) 0.95†
   Left 132 (41.5) 421 (41.6)
   Right 171 (53.8) 545 (54.0)
   Both 16 (4.7) 45 (4.4)
Emergency surgery 0 117 (36.8) 325 (32.1) 0.12†
Duration of surgery (min) 4 (0.3) 180 [125–230] 180 [135–240] 0.68‡
Duration of anesthesia (min) 4 (0.3) 180 [125–230] 180 [135–240] 0.34‡
Requirement of OLV 4 (0.3) 274 (86.2) 904 (89.6) 0.09†
Duration of OLV (min) 135 [70–190] 110 [40–170] 0.01‡
Receiving TEA/TPB 9 (0.7) 102 (32.2) 338 (33.6) 0.63†
Total fluid intake (mL) 3 (0.2) 800 [450–1,250] 800 [500–1,070] 0.26‡
Total crystalloid (mL) 3 (0.2) 700 [400–1,050] 735 [450–1,070] 0.12‡
Total colloid (mL) 3 (0.2) 0 [0–0] 0 [0–0] 0.89‡
Total HES (mL) 0 [0–0] 0 [0–0] 0.95‡
   ≤1,000 309 (97.2) 1,001 (99.1) 0.02†
   >1,000 9 (2.8) 10 (0.9)
Total blood loss (mL) 100 [50–300] 100 [50–300] 0.12‡
Total PRC transfusion (mL) 0 0 [0–0] 0 [0–0] 0.19‡
Hypercarbia 3 (0.2) 68 (24.7) 250 (21.4) 0.22†
Hypoxemia 3 (0.2) 17 (5.3) 39 (3.8) 0.25†
Hypotension 5 (0.4) 67 (21.1) 244 (24.2) 0.25†
Lowest MAP (mmHg) 6 (0.4) 61.3 [55–68.3] 60 [56–68.3] 0.79‡
Duration of hypotension (min) 4 (0.3) 5 [0–5] 5 [0–5] 0.42‡
Intraoperative vasopressor
   Epinephrine (mg) 5 (0.4) 6 [0–18] 6 [0–15] 0.58‡
   Norepinephrine (µg) 5 (0.4) 0 [0–0] 0 [0–0] 0.006‡
Intraoperative urine output (mL/kg/h) 31 (2.3) 1.0 [0.5–1.8] 1.3 [0.7–2.2] <0.001‡

Categorical data are presented as n (%). Non-normal data are presented as median and interquartile range [25th–75th percentile]. †, Chi-squared test; ‡, Mann-Whitney U test. AKI, acute kidney injury; HES, hydroxyethyl starch; MAP, mean arterial pressure; OLV, one lung ventilation; PRC, pack red cell; TEA, thoracic epidural anesthesia; TPB, thoracic paravertebral block; VATS, video-assisted thoracoscopic surgery.