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Subcellular localization of the full-length SIRT3 gene in Cos7 cells. A shows DAPI staining of the nuclei, and B depicts the localization of the SIRT3-EGFP protein. Shown in red in C is the mitochondrial marker, Mitotracker. D shows superimposed images of A–C. It is clear from D that SIRT3 localizes to the mitochondria.
