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. 2026 Feb 11;13:e39. doi: 10.1017/gmh.2026.10151

Table 2.

Mediation analysis results: PC as a mediator of the relationship between pain intensity and depression.

Path Coefficient SE 95% CI p-value
Total effect (c) 1.289 0.267 (0.763, 1.814) <.0001*
Direct effect (c’) 0.340 0.258 (−0.168, 0.849) 0.1887
Indirect effect (a × b) 0.948 0.166 (0.652, 1.288) <.0001*
Path a (NRS → PCS) 2.344 0.313 (1.727, 2.961) <.0001*
Path b (PCS → Depression) 0.404 0.046 (0.315, 0.494) <.0001*

* p-value < 0.05.