Table 3. MIC values (µM) determined for 1, 3, 5, 7, and 9, and 1 : 1 enantiomeric mixtures of 3 + 5 and 7 + 9 against four different S. aureus strains: ATCC 9144; NCTC 13616; USA300; 1199B. Where SSAs are supplied as mixtures, the concentrations reported represent the total molecular concentration. The values calculated represent absolute values, obtained from two biological repeat experiments, each containing three technical repeats, after 900 min. Please see SI Section S18 for MIC data, specifically summary Table S15. MIC of ciprofloxacin (CP) is provided in µg mL−1.
| SSA | ATCC 9144 | NCTC 13616 | USA300 | 1199B |
|---|---|---|---|---|
| 1 | 1390 | >2780 | >2780 | >2780 |
| 3 | 87 | 87 | >2780 | 87 |
| 5 | 174 | 87 | >2780 | 2780 |
| 7 | 87 | 87 | 87 | 174 |
| 9 | 174 | 87 | 87 | 174 |
| 3 + 5 | 174 | 87 | 174 | 174 |
| 7 + 9 | 87 | 87 | 87 | 87–349 |
| CIP | 1 | 128 | 64 | 8 |