Table 1.
Demographic characteristics of the participants from ADNI dataset
| AD (N = 314) | CN (N = 500) | P value | |
|---|---|---|---|
| Age, mean (SE), years | 74.79 (0.44) | 74.23 (0.26) | 0.052 |
| Gender, F/M, n | 144/170 | 256/244 | 0.16 |
| Race, White/Black/Asian/≥2 | 290/13/7/4 | 455/32/8/5 | 0.50 |
| Education, mean (SE), years | 15.14 (0.17) | 16.41 (0.12) | 3.11e-09*** |
| APOEε4, 0/1/2, n | 106/146/62 | 358/130/12 | 2.2e-16*** |
| Total intracranial volume, cm3 | 1535.71 (10.32) | 1512.22 (7.00) | 0.20 |
Note: Values are expressed as the mean (SE). The p values for the comparison between AD and CN were determined using the Wilcoxon rank-sum test. The Chi-square test was utilized to examine associations among gender, race, and the presence of the APOEε4 risk allele. p values are presented without correction for multiple comparisons. Significance levels are denoted by asterisks (* p < 0.05, ** p < 0.01, *** p < 0.001). Abbreviations: AD, Alzheimer’s Disease; APOE, apolipoprotein E; CN, cognitively normal