Table 2.
Basic demographic1, exposure and outcome variables in full analytical sample, stratified by ancestry and year
| EU sample (sample 1) | Year 0 (n = 6,336) | Year 2 (n = 4,617) |
|---|---|---|
| Mean cortical thickness (mean (s.d.)2) | 2.74 (0.08) | 2.70 (0.08) |
| Depression (mean (s.d.)) | 53.60 (5.66) | 53.94 (6.02) |
| Internalizing (mean (s.d.)) | 48.70 (10.45) | 48.30 (10.33) |
| Externalizing (mean (s.d.)) | 45.42 (10.01) | 44.47 (9.65) |
| Polygenic score for CRP (mean (s.d.)) | −0.18 (0.93) | −0.18 (0.93) |
| Age (years) | 9.92 (0.63) | 11.96 (0.65) |
| Sex at birth, female (%) | 2,982 (47.1%) | 2,080 (45.1%) |
| Body mass index (mean (s.d.)) | 17.92 (3.31) | 19.69 (4.01) |
| Non-EU sample (sample 2) | Year 0 (n = 4,878) | Year 2 (n = 3,206) |
| Mean cortical thickness (mean (s.d.)) | 2.70 (0.08) | 2.66 (0.08) |
| Depression (mean (s.d.)) | 53.61 (5.80) | 53.55 (5.83) |
| Internalizing (mean (s.d.)) | 48.19 (10.91) | 46.96 (10.76) |
| Externalizing (mean (s.d.)) | 46.26 (10.74) | 44.81 (10.18) |
| Polygenic score for CRP (mean (s.d.)) | 0.25 (1.04) | 0.24 (1.03) |
| Age (years) | 9.90 (0.62) | 11.94 (0.66) |
| Sex at birth, female (%) | 2,347 (48.1%) | 1,511 (47.1%) |
| Body mass index (mean (s.d.)) | 19.78 (4.46) | 21.66 (4.80) |
| Full meta-analysis sample | Year 0 (n = 11,214) | Year 2 (n = 7,823) |
| Mean cortical thickness (mean (s.d.)) | 2.72 (0.08) | 2.69 (0.08) |
| Depression (mean (s.d.)) | 53.60 (5.72) | 53.78 (5.95) |
| Internalizing (mean (s.d.)) | 48.48 (10.66) | 47.75 (10.53) |
| Externalizing (mean (s.d.)) | 45.77 (10.34) | 44.63 (9.87) |
| Polygenic score for CRP (mean (s.d.)) | 0.00 (1.00) | −0.01 (1.00) |
| Early-life infection, yes (%) | 1,710 (16.7%) | 1,218 (16.9%) |
| Age (years) | 9.91 (0.63) | 11.95 (0.65) |
| Sex at birth, female (%) | 5,329 (47.5%) | 3,591 (45.9%) |
| Body mass index (mean (s.d.)) | 18.73 (3.96) | 20.49 (4.45) |
1Owing to page limitations, detailed socioeconomic variables (race/ethnicity, parental education and household income) are presented in Supplementary Table 14.
2s.d., standard deviation.