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. 2005 Aug 9;9(5):R549–R555. doi: 10.1186/cc3794

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Copyright © 2005 Schumacher et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Ex vivo production of interleukin-6. Preoperative and postoperative (po) interleukin (IL)-6 levels in whole blood culture supernatant. Values are expressed as means and SEM (error bars). IL-6 production was significantly increased after stimulation with lipopolysaccharide (LPS; white), in comparison with the unstimulated control (C; black) at all time points. In comparison with preoperative levels, IL-6 production after stimulation with LPS significantly decreased 5 days after operation (P < 0.002) but again reached preoperative levels 10 days after operation.