Fig. 4.

ydgT mutants have a biphasic systemic virulence phenotype. (A) Groups of mice were infected with a mixed inoculum of ΔydgT and wild-type Salmonella, and the CI for the ydgT^- strain were determined in the MLN, liver, and spleen. The CI of the chromosomally marked Cm-resistant SL1344 strain (SL1344 ushA::cat) compared to the unmarked SL1344 parent strain are shown (A Inset). Each data point represents one animal, and horizontal bars indicate means. CI, P < 0.001 (24 and 55 h) for all organs. (B and C) CI of ssrB::aphT ΔydgT double mutants and each of the single mutants at 24 h after infection. Each datum represents one animal, bars indicate means.