Table 1. Cardiac properties of mice with ablation of skMLCK.
Mouse | Body weight, g | Heart weight, mg | Heart/body weight ratio | RLC phosphorylation, mol P/mol RLC |
---|---|---|---|---|
Wild-type | 22.13 ± 1.36 | 111 ± 14.7 | 5.07 ± 0.12 | 0.44 ± 0.02 |
skMLCK knockout | 24.21 ± 1.07 | 132 ± 9.1 | 5.45 ± 0.11 | 0.40 ± 0.01 |
Heart weight, body weight, and cardiac RLC phosphorylation were measured as described in Methods. Values are means ± SEM for at least five values. P, phosphate.