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. 2026 Mar 5;17(2):237–246. doi: 10.14740/wjon2728

Table 3. Long-Term Renal Functional Outcomes (N = 68).

Outcome RN group (N = 31) PN group (N = 37) P-value
Mean follow-up duration 45.7 ± 15.8 months
Pre-operative eGFR (baseline) (mL/min/1.73 m2) 49.8 ± 6.7 48.8 ± 11.1 0.522
Long-term eGFR (endpoint) (mL/min/1.73 m2) 26.5 ± 7.3 36.8 ± 10.8 -
Total eGFR decline (mL/min/1.73 m2) −23.3 ± 6.0 −13.2 ± 3.5 < 0.001
CKD stage progression rate in F/U (%) 100% (31/31) 62.2% (23/37) 0.004
Subgroup: pre-operative eGFR ≥ 45 mL/min/1.73 m2 RN group (N = 23) PN group (N = 27) P-value
Pre-operative eGFR (baseline) (mL/min/1.73 m2) 53 ± 3.9 54.5 ± 4.1 0.124
Long-term eGFR (endpoint) (mL/min/1.73 m2) 28.3 ± 7.2 41.0 ± 6.9 -
eGFR decline (mL/min/1.73 m2) −24.7 ± 5.3 −13.5 ± 3.8 < 0.001
Subgroup: pre-operative eGFR < 45 mL/min/1.73 m2 RN group (N = 8) PN group (N = 10) P-value
Pre-operative eGFR (baseline) (mL/min/1.73 m2) 40.5 ± 3.5 33.2 ± 8.7 0.083
Long-term eGFR (endpoint) (mL/min/1.73 m2) 21.3 ± 5.1 20.8 ± 8.3
eGFR decline (mL/min/1.73 m2) −19.3 ± 6.5 −12.4 ± 2.5 0.002

This table demonstrates the long-term functional advantage of PN over RN, particularly regarding the magnitude of eGFR decline. eGFR: estimated glomerular filtration rate; PN: partial nephrectomy; RN: radical nephrectomy.