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ENG mitigated DOX-triggered oxidative stress and improved of mitochondrial function. (A–C) Representative images and quantitative analysis of DHE staining of cardiomyocytes (n = 6) and 4-HNE staining of mice cardiac tissue (n = 5). (D) MDA level in mice serum (n = 5). (E) Representative images of mitochondria from the myocardium of mice in each group. Statistical analysis was performed using one-way ANOVA, followed by Tukey’s post hoc test. *P < 0.05, **P < 0.01, ***P < 0.001.
