Table 1. Demographics and clinical characteristics of OFC-positive and OFC-negative patients.

	Positive (n = 24; 67%)	Negative (n = 12; 33%)
Age (mean, range)	40 years (± 1 2), 19 – 61	37 years (± 15), 20 – 61
Sex	Female: n = 12 (50%) Male: n = 12 (50%)	Female: n = 6 (50%) Male: n = 6 (50%)
Wheat allergy status	Suspected: n = 2 (8%) Physician confirmed: n = 22 (92%)	Suspected: n = 4 (33%) Physician confirmed: n = 8 (67%)
Self-reported systemic reaction to wheat	No: n =2 (8%) Yes: n = 22 (92%)	No: n = 5 (42%) Yes: n = 7 (58%)
Cofactor-dependent wheat allergy	No: n = 7 (30%) Yes: n = 16 (70%)	No: n = 7 (58%) Yes: n = 5 (42%)
Sampson-Score pre OFC (1 – 5) Muraro-Score pre OFC (1 – 3)	Median: 4 (range: 1 – 4) Median: 3 (range: 1 – 3)	Median: 3.5 (range: 3 – 4) Median: 3 (range: 3 – 3)
Life years with diagnosis	Median: 2.49 years Range: 0.05 – 11.03 years	Median: 4.05 years Range: 0.19 – 20.76 years
Atopic comorbidities	Allergic rhinoconjunctivitis (n = 6), asthma (n = 1), eczema (n = 3)	Allergic rhinoconjunctivitis (n = 8), asthma (n = 0), eczema (n = 0)
Elicitors of allergic rhinoconjunctivitis	Grass pollen (n = 6), weed pollen (n = 5), animals (n = 1), house dust mite (n = 1), mold (n = 1)	Grass pollen (n = 7), weed pollen (n =7), animals (n = 5), house dust mite (n = 4), mold (n = 2)
Avoidance of other cereals and cultivars than common wheat	Spelt (n = 9), rye (n = 7), emmer (n = 3), einkorn (n = 1), oat (n = 2), barley (n = 2)	All cereal (n = 3), spelt (n = 2), rye (n = 2)

OFC = oral food challenge.