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. 2026 Feb 27;16:1748250. doi: 10.3389/fonc.2026.1748250

Table 2.

Operative characteristics of HCCA patients with PVR and non-PVR.

Variables Total Non-PVR PVR P
(n = 317) (n = 255) (n = 62)
Blood loss (mL) 771.32 ± 604.98 744.06 ± 575.95 887.27 ± 709.34 0.102
Tumor diameter (cm) 5.38 ± 18.36 5.32 ± 19.32 5.60 ± 14.06 0.918
Bismuth ≥ III, n (%) 224 (71.57) 168 (66.93) 56 (90.32) <0.001
Large-scale liver resection, n (%) 197 (69.61) 144 (64.57) 53 (88.33) <0.001
Blood transfusion, n (%) 192 (61.34) 151 (59.92) 41 (67.21) 0.294
Portal vein invasion, n (%) 102 (32.18) 43 (16.86) 59 (95.16) <0.001
Hepatic artery invasion, n (%) 76 (23.97) 43 (16.86) 33 (53.23) <0.001
Hepatic artery reconstruction, n (%) 28 (8.83) 14 (5.49) 14 (22.58) <0.001
Poor differentiation, n (%) 61 (19.93) 48 (19.59) 13 (21.31) 0.764
Lymph node metastasis, n (%) 115 (36.51) 86 (33.99) 29 (46.77) 0.061
Ki67 (%) 21.75 ± 15.41 22.53 ± 15.40 18.89 ± 15.31 0.198
Endoscopic vascular invasion, n (%) 31 (9.84) 23 (9.06) 8 (13.11) 0.339
Endoscopic nerve invasion, n (%) 134 (42.81) 110 (43.65) 24 (39.34) 0.542

HCCA, hilar cholangiocarcinoma; PVR, portal vein reconstruction.