Table 1.

Distribution of germ line and somatic RB1 mutations by phenotype of the patients.

	Germ line	Somatic	Total
Bilateral sporadic	424	24	448
Bilateral familiar	99		99
Low penetrance	27		27
Unilateral sporadic	52	131	183
Unilateral familiar	6		6
Not reported	145		145
Total	753	155	908