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. 2026 Mar 5;15(5):464. doi: 10.3390/cells15050464
α-SMA α-smooth muscle actin
AF-1 Activation function-1 domain
AF-2 Activation function-2 domain
ALP Alkaline phosphatase
AMPK AMP-activated protein kinase
ApoAI Apolipoprotein AI
ApoAII Apolipoprotein AII
ApoAIV-V Apolipoprotein AIV-V
ApoB100 Apolipoprotein B100
ApoCI Apolipoprotein CI
CCl4 Carbon tetrachloride
CD-HFD Choline-deficient high-fat diet
CETP Cholesteryl ester transfer protein
CVD Cardiovascular disease
ECM Extracellular matrix
EphB4 Ephrin receptor B4
ER Endoplasmic reticulum
ERK1/2 Extracellular signal-regulated kinase 1/2
FGF21 Fibroblast growth factor 21
GLP-1 Glucagon-like peptide 1
GDF15 Growth differentiation factor 15
HDL High-density lipoprotein
HFD High-fat diet
HSC Hepatic stellate cell
HCC Hepatocellular carcinoma
hs-CRP high-sensitivity C-reactive protein
IL Interleukin
InsRβ Insulin receptor beta subunit
IRS Insulin receptor substrate
LBD Ligand-binding domain
LDL Low-density lipoprotein
LPS lipopolysaccharide
LSECs liver sinusoidal endothelial cells
MAPK Mitogen-activated protein kinase
MRI Magnetic resonance imaging
MASH Metabolic dysfunction–associated steatohepatitis
MASLD Metabolic dysfunction–associated steatotic liver disease
mTOR Mammalian target of rapamycin
NEFAs Non-esterified fatty acids
NLRP3 nucleotide-binding and oligomerization domain (NOD)-like receptor family pyrin domain-containing 3
NF–κB Nuclear factor kappa-light-chain-enhancer of activated B cells
NPC1L1 Niemann-Pick C1-Like 1 protein
PBC primary biliary cholangitis
PC-TP Phosphatidylcholine transfer protein
PGC-1α PPAR-γ coactivator 1 alpha
PI3K Phosphatidylinositol 3-kinase
PKA protein kinase A
PPAR Peroxisome proliferator-activated receptor
PPRE Peroxisome proliferator response element
RXR Retinoid X receptor
SREBP-1c Sterol regulatory element binding protein 1c
SCFA Short-chain fatty acids
SMAD Suppressor of mothers against decapentaplegic
SOCS3 suppressor of cytokine signaling 3
STAT Signal transducer and activator of transcription
TCPTP45 T-cell protein tyrosine phosphatase 45
T2DM Type 2 diabetes mellitus
TG Triglyceride
TGF-β Transforming growth factor beta
UDCA Ursodeoxycholic acid
VLDL Very low-density lipoprotein