BBB	Blood–brain barrier
BSA	Bovine serum albumin
CHI3L1	Chitinase-3-like protein 1
CIS	Clinically isolated syndrome
CLP	Chitinase-like protein
CNS	Central nervous system
CSF	Cerebrospinal fluid
DAPI	4′,6-diamidino-2-phenylindole
DMF	Dimethyl fumarate
DPBS	Dulbecco’s phosphate-buffered saline
EAE	Experimental autoimmune encephalomyelitis
EBV	Epstein–Barr virus
EDSS	Expanded disability status scale
EDTA	Ethylenediaminetetraacetic acid
ELISA	Enzyme-linked immunosorbent assay
GH18	Glycosyl hydrolase family 18
HC	Healthy controls
HL-60	Human promyelocytic leukemia cell line
KHCO3	Potassium bicarbonate
MFI	Mean fluorescence intensity
MDM	Disease-modifying drug
MMP-9	Matrix metalloproteinase 9
MPO	Myeloperoxidase
MRI	Magnetic resonance imaging
MS	Multiple sclerosis
NDS	Normal donkey serum
NET	Neutrophil extracellular trap
NH4Cl	Ammonium chloride
NK	Natural killer
Nrf2	Nuclear factor erythroid 2-related factor 2
PBMCs	Peripheral blood mononuclear cells
PBS	Phosphate-buffered saline
px	pixel
RBCs	Red blood cells
RRMS	Relapsing-remitting multiple sclerosis
RT	Room temperature
TNFα	Tumor necrosis factor alpha