MOE	Melissa officinalis extract
SD	Standard diet
HFHSD	High-fat high-sucrose diet
HFHSD MOE	HFHSD supplemented with MOE
EPM	Elevated plus maze
OGTT	Oral glucose tolerance test
AUC	Area under the curve
GABA	γ-aminobutyric acid
GABA-T	γ-aminobutyric acid transaminase
ONIRIS	Nantes-Atlantic National College of Veterinary Medicine, Food Science and Engineering
BW	Body weight
BMI	Body mass index
AI	Adiposity index
VAT	Visceral adipose tissue
AC	Abdominal circumference
SEM	Standard error of the mean
HPO	Hydrophobic extract
HPI	Hydrophilic extract
ESI	Electrospray ionization
OPLS-DA	Orthogonal partial least squares–discriminant analysis
VIP	Variable importance in projection
KEGG	Kyoto Encyclopedia of Genes and Genomes
SMPDB	Small Molecule Pathway Database
UHPLC	Ultra-high-performance liquid chromatography
QTOF-HRMS	Quadrupole time-of-flight-high resolution mass spectrometry
HMDB	Human Metabolome Database
MoNA	MassBank of North America
OLETF	Otsuka Long-Evans Tokushima fatty
PPP	Pentose phosphate pathway
BA	Bile acids
FXR	Faresoid X receptor
TGR5	Takeda G protein-coupled receptor 5