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. 2025 May 6;283(2):1201–1213. doi: 10.1007/s00405-025-09436-3

Table 2.

Aerobic exercise protocols of the included studies

Author & Year Exercise program in aerobic exercise group Control group treatment
Intervention Frequency Intensity Time Type
Ackel-D’ Elia et al., 2011 Aerobic Exercise + CPAP 3 times/week for 8 weeks 85% of Anaerobic Threshold 60 min Treadmill walking or Running CPAP for 8 weeks
Carneiro-Barrera et al., 2022 Nutritional behavior change, moderate aerobic exercise, smoking cessation, alcohol intake avoidance, and sleep hygiene Daily for 8 weeks (Supervised once a week) 55–65% of HRR 60 min Walking General advise on weightloss and lifestyle change
Foster et al., 2009 Behaviouralweightloss program + moderate intensity aerobic exercise 7 days/ week for 1 year moderate intensity 175 min/week brisk walking Diabetes support and education
Jurado-Garcia et al., 2020 Graduated Walking Program 5 times/week for 24 weeks Borg Scale for Perceived Exertion − 1–4 weeks: 9–11 for warm up and cool down,11–14 for training; 5–24 weeks: 9–11 for warm up and cool down, 12–15 for training 1–2 weeks: 5 min warm up, 20 min training, 5 min cool down; 3–4 weeks: 5 min warm up, 30 min training, 5 min cool down; 5–24 weeks: 5 min warm up, 45 min training, 5 min cooldown Walking General therapeutic measures and regular physical activity recommended
Karlsen et al., 2017 Supervised High Intensity Interval Training 2 times/week for 12 weeks warm up: 70% of HRmax, Exercise training: 90–95% of HRmax, After last interval: 70% of HRmax 10 min warm up, 4*4 min exercise training, 3 min at last Treadmill walking or Running Continue normal lifestyle
Lins-Filho et al., 2023 High Intensity Interval Training 3 times/week for 12 weeks warm-up and cool-down at ~ 40% of HRmax, 5 cycles of 4 min walking or running between 90% and 95% of maximum heart rate (HRmax) interspersed by 3 min of walking at 50–55% of HRmax 4 min warmup, 35 min exercise, 4 min cool down Treadmill walking or Running Stretching activity + adviced unsupervised 30 min physical activity
Sengul et al., 2011 Aerobic exercise and breathing exercise 3 times/week for 12 weeks 60–70% of VO2max 45–60 min Bicycle Ergometer & Treadmill No treatment
Yang et al., 2018 Supervised Exercise Training 3 times/week for 12 weeks At VO2 (Anaerobic Threshold) 15 min warm up, 15 min cool down, 30 min exercise Bicycle Ergometer Maintained previous lifestyle