Table 3.
EEG and cognitive function improvements in the KD and Control groups over 6 months.
| Control group (n = 63) | KD group (n = 73) | OR (95%CI) | P | |
|---|---|---|---|---|
| EEG | 2.83 (1.32–6.06) | <0.001 | ||
| Seizure improvement | 7.9 (5/63) | 11.0 (8/73) | ||
| Interictal improvement | 15.9 (10/63) | 15.1 (11/73) | ||
| Interictal and seizure improvement | 6.3 (4/64) | 31.5 (23/73) | ||
| No improvement | 69.8 (44/63) | 42.5 (31/73) | ||
| Cognitive result | ||||
| Overall cognitive improvement | 19.0 (12/63) | 35.6 (26/73) | 2.79 (1.17–6.43) | 0.03 |
| Griffths developmental domains (0–8 years) | ||||
| Gross motor improvement | 10.9 (5/46) | 28.8 (15/52) | 3.32 (1.10–10.04) | 0.04 |
| Personal-social improvement | 8.7 (4/46) | 25.0 (13/52) | 3.50 (1.05–11.65) | 0.09 |
| Language improvement | 13.0 (6/46) | 30.8 (16/52) | 2.96 (1.05–8.39) | 0.04 |
| Eye-hand coordination improvement | 8.7 (4/46) | 25.0 (13/52) | 3.50 (1.05–11.65) | 0.09 |
| Performance improvement | 10.9 (5/46) | 28.8 (15/52) | 3.32 (1.10–10.04) | 0.04 |
| WISC cognitive outcome (≥ 8 years) | ||||
| Full-Scale IQ increase ≥ 5 points | 17.6 (3/17) | 33.3 (7/21) | 2.33 (0.50–10.91) | 0.28 |