Table 2.

Comparisons of plasma concentrations

Serial number	Time points of sampling (h)	Plasma concentrations (ng/mL)				CV of the plasma concentrations (%)
Serial number	Time points of sampling (h)	Fasting (n = 56)	Fed (n = 58)	P value	Fasting/fed	Fasting (n = 56)	Fed (n = 58)
1	0	BQL	BQL	/	/	/	/
2	0.25	26.9 ± 31.9	8.2 ± 13.4	<0.001^*	3.28	118.45	162.73^#
3	0.5	102.6 ± 61.0	34.2 ± 31.0	<0.001^*	3.00	59.44	90.61^#
4	1	165.7 ± 60.6	72.9 ± 49.5	<0.001^*	2.27	36.59	67.83^#
5	1.25	167.5 ± 44.1	87.4 ± 39.2	<0.001^*	1.92	26.34	44.90^#
6	1.5	163.2 ± 35.6	95.7 ± 33.7	<0.001^*	1.71	21.83	35.25^#
7	1.75	157.9 ± 32.4	94.1 ± 28.1	<0.001^*	1.68	20.49	29.86^#
8	2	151.8 ± 27.3	94.2 ± 26.3	<0.001^*	1.61	18.02	27.88^#
9	2.25	148.2 ± 28.2	91.5 ± 22.6	<0.001^*	1.62	19.02	24.71^#
10	2.5	138.0 ± 21.9	85.3 ± 18.8	<0.001^*	1.62	15.86	22.05^#
11	2.75	130.5 ± 18.5	83.9 ± 16.0	<0.001^*	1.55	14.18	19.04^#
12	3	123.3 ± 17.9	79.4 ± 15.0	<0.001^*	1.55	14.55	18.86^#
13	4	104.4 ± 16.4	74.4 ± 11.1	<0.001^*	1.40	15.73	14.92
14	6	72.0 ± 12.5	53.1 ± 8.8	<0.001^*	1.36	17.39	16.57
15	8	52.6 ± 9.1	40.5 ± 7.6	<0.001^*	1.30	17.28	18.77^#
16	10	40.4 ± 8.2	32.7 ± 6.7	0.002^*	1.24	20.42	20.60^#
17	12	30.7 ± 6.5	25.4 ± 4.9	0.004*	1.21	21.20	19.43
18	24	10.1 ± 3.0	9.3 ± 1.8	0.281	1.09	29.27	19.63
19	36	3.5 ± 1.4	3.2 ± 1.2	0.483	1.09	39.44	35.97
20	48	2.2 ± 0.9	2.2 ± 0.8	0.839	1.03	40.19	34.66

Notes: *p < 0.01, plasma concentration of the fasting vs the fed. ^#CV of the fed was higher than that of the fasting. CV, coefficient of variation