. 2004 Jun;5(6):567–571. doi: 10.1038/sj.embor.7400172

Table 1.

Twenty-two open-reading frames in the genome of Saccharomyces cerevisiae with well-conserved J domains

J protein	Gene	Length^{^*}	J domain^{^†}	Type	TM^{^§}	Subcellular location	Function (known or predicted)
Ydj1	Ynl064c	409	4–72	I	0	Cytoplasm	Protein folding
Xdj1	Ylr090w	459	7–79	I	0	Cytoplasm	Protein folding
Apj1	Ynl077w	528	4–73	I	0	Cytoplasm	Protein folding
Sis1	Ynl007c	352	4–70	II	0	Cytoplasm	Translation initiation
Djp1	Yir004w	432	4–72	II	0	Cytoplasm	Peroxisome biogenesis
Zuo1	Ygr285c	433	98–170	III	0	Cytoplasm	Translation and folding
Swa2	Ydr320c	668	604–668	III	0	Cytoplasm	Clathrin uncoating
Jjj1	Ynl227c	590	2–72	III	0	Cytoplasm	Endocytosis (?)
Jjj2	Yjl162c	482	11–79	III	0	Cytoplasm	Unknown
Jjj3	Yjr097w	172	6–78	III	0	Cytoplasm	Unknown
Caj1	Yer048c	391	4–73	II	0	Nucleoplasm	Ca²⁺-dependent function (?)
Cwc23	Ygl128c	347	84–153	III	0	Nucleoplasm	mRNA splicing
Mdj1	Yfl016c	511	59–127	I	0	Mitochondria	Protein folding
Mdj2	Ynl328c	146	90–146	III	1	Mitochondria	Mitochondrial biogenesis
Pam18	Ylr008c	168	109–168	III	1	Mitochondria	Protein translocation
Jac1	Ygl018c	184	18–84	III	0	Mitochondria	Iron–sulphur cluster assembly
Jid1	Ypr061c	301	62–153	III	1	Mitochondria	Unknown
Scj1	Ymr214w	404	48–117	I	0	ER	Protein folding
Hlj1	Ymr161w	234	19–87	II	1	ER	Protein degradation
Jem1	Yjl073w	645	536–610	III	0	ER	Karyogamy, protein folding
Sec63	Yor254c	663	123–198	III	3	ER	Protein translocation
Erj5	Yfr041c	295	42–110	III	2	ER	Unknown

Iterative BLAST searches, starting with the J domain of DnaJ.

^*The number of amino-acid residues in the open-reading frame.

^†The position of the J domain in terms of the first and the last residue.

^§The number of transmembrane (TM) segments predicted for each protein using the DAS algorithm (see the DAS Transmembrane Prediction server online at http://www.sbc.su.se/%7Emiklos/DAS/maindas.html). The subcellular location is given, along with the function or predicted function (references compiled in the Saccharomyces Genome Database, available online at http://www.yeastgenome.org). ER, endoplasmic reticulum; mRNA, messenger RNA.