Table 1.
Observed distribution of stop-EGFP revertant mutations in four lobes of the liver
Lobe | Mutation count | Cell count | Mutation frequency |
---|---|---|---|
Left caudal |
12 |
(6.61±2.32) × 107 |
(1.82±3.04) × 10−7 |
Right anterior |
6 |
(3.06±0.84) × 107 |
(1.96±0.25) × 10−7 |
Left anterior |
1 |
(2.04±0.32) × 107 |
(0.49±0.25) × 10−7 |
Right caudal |
7 |
(2.18±0.43) × 107 |
(3.21±0.84) × 10−7 |
All | 26 | (13.89±1.99) × 107 | (1.87±0.27) × 10−7 |
The cell count is the estimated total number of cells in each lobe and the mutation frequency is the total number of mutations divided by the total number of cells. The total number of cells in each lobe was estimated by multiplying the total cell number in a reference slice by the total number of slices of a similar size sectioned from the organ.