Figure 2.

The endocytic network. Schematic representation of the complex protein network involved in the formation of clathrin-coated vesicles at the plasma membrane. Interactions mediated by the clathrin N-terminal domain (red), the α-appendage (blue), β-appendage (green), μ-subunit (pink) of adaptor protein 2 (AP2) are shown. Interactions among accessory proteins are indicated in grey. Cargo-specific adaptors are represented in brown.