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. 2026 Mar 17. Online ahead of print. doi: 10.1039/d5sc09702a

Table 1. Slopes for the linear regression analysis in Fig. 4 and S15 showing the increase in average charge state of Ab and Ab·Prn complex as a function of solution temperature.

Antibody Slope for increase in average charge state of free antibody (r2) Slope for increase in average charge state of 1 : 1 mAb·Prn complex (r2)
2E9 0.020 + 0.007 0.962 0.040 + 0.001 0.987
1E7 0.027 + 0.001 0.945 0.063 + 0.001 0.984
1F2 0.032 + 0.001 0.993 0.047 + 0.003 0.993
2B1 0.05 + 0.01 0.995 0.054 + 0.002 0.987