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. 2026 Feb 27;29(4):115137. doi: 10.1016/j.isci.2026.115137

Figure 2.

Figure 2

Quantitative analysis of OCT4A and PG1 expression in early-stage endometrial cancer tissue samples

(A) The gene expression levels of OCT4A and PG1 in each clinical sample and their respective clinical and pathological background findings are shown. Patient background information is presented in Table S1. Gene expression levels are represented as 2−ΔCT values using HPRT1 as the endogenous control. The color intensity in the Figure represents the relative gene expression levels. The expression level data for each sample are shown in Figure S4.

(B) OCT4A and PG1 expression and their correlation with the clinical background.

(C) OCT4A and PG1 expression and their correlations with pathological findings. Each data point represents the mean of the triplicate measurements. Statistical processing was performed using the Mann-Whitney U and Kruskal-Wallis tests. Statistical significance was defined as p < 0.05. ∗ = p < 0.05, ∗∗ = p < 0.01, ∗∗∗ = p < 0.001, and ∗∗∗∗ = p < 0.0001. (−) = absent, (+) = positive. DM, diabetes mellitus; SQ, squamous differentiation; MI, myometrial invasion; CI, cervical stromal invasion; LVSI, lymphovascular space invasion; MELF, microcystic, elongated, and fragmented; ascites, ascites cytology.