Figure 8.

Effects of β1-CD4 expression on the activation of the prolactin/STAT5 and the NFκB signaling pathways in COS7 cells. Cells were transiently cotransfected with plasmids encoding PRLR and STAT5A, and, when mentioned, with the psp72-MMTV, MMTV-β1-CD4, or MMTV-CD4 plasmids. (A) β-Casein gene promoter-luciferase reporter activity. (B) NFκB-luciferase reporter activity. In each case, the data shown are the results of a representative experiment performed in duplicate. Mean values are presented with SD indicated by bars.