Developmental changes of anti-CNG1 and sense CNGα1 expression in human cerebral cortex. (A–D) Anti-CNG1 expression in visual cortex; (E–H) CNGα1 expression in visual cortex; (I–L) anti-CNG1 expression in frontal cortex; (M–P) CNGα1 expression in frontal cortex. A, E, I, and M show samples of fetal cerebral cortex; B, F, J, and N show samples of adult cerebral cortex. D, H, L, and P are high-magnification pictures taken from adult cortical layer III/II; C, G, K, and O show control experiments. O, outermost layer; M, middle layer; In, inner layer; I–VI, cortical layers I to VI; PC, pyramidal cells.