Table 1.
Group |
Total Cell #(X105) |
No. | CD44+ CD25- | CD44+ CD25+ | CD44- CD25+ | CD44- CD25- | CD4+ CD8+ CD3+ |
In All DN |
wt Adult | NC | 8 | 2.04 ± 0.53* | 15.83 ± 1.73* | 15.38 ± 3.36* | 34.73 ± 11.43 | 6.07 ± 1.19* | 18.4 ± 5.14* |
wt Fetal | 42.72 ± 3.88 | 23 | 18.05 ± 8.67 | 20.99 ± 10.66 | 22.82 ± 8.33 | 41.78 ± 14.87 | 19.05 ± 8.12 | 27.6 ± 8.79 |
Pax1+/- | 32.14 ± 2.15 | 22 | 14.86 ± 8.97 | 19.12 ± 6.985 | 16.70 ± 5.47 | 35.32 ± 14.82 | 20.80 ± 10.0 | 24.3 ± 7.38 |
Hoxa3+/- | 29.25 ± 3.43 | 13 | 18.06 ± 9.20 | 22.87 ± 11.45 | 19.14 ± 8.73 | 29.89 ± 15.17 | 17.02 ± 10.04 | 21.2 ± 7.23 |
Pax1-/- | 22.38 ± 4.98 | 4 | 18.97 ± 11.50 | 21.67 ± 4.10 | 26.31 ± 7.35 | 45.59 ± 16.90 | 28.61 ± 9.46 | 24.8 ± 9.05 |
Hoxa3+/-Pax1-/- | 7.96 ± 1.12 | 6 | 19.58 ± 8.52 | 25.28 ± 5.55 | 22.79 ± 4.56 | 44.87 ± 14.15 | 35.37 ± 6.414 | 25.8 ± 6.54 |
RAGnull | UC | 14 | 16.57 ± 3.12 | 37.70 ± 7.89** | 14.33 ± 3.16** | - | - | 11.2 ± 3.3** |
* P < 0.01, significant differences between wild type fetal and adult.
** P < 0.01, significant differences with fetal wild type.
*** NC: not count.