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. 2026 Mar 17;17(3):662–678. doi: 10.7150/jca.130519

Figure 2.

Figure 2

Pan-cancer expression profiles of CHI3L family genes with focus on GBM. Box-and-scatter plots show the expression levels of (A) CHI3L1, (B) CHI3L2, (C) CHIA, (D) CHID1, and (E) CHIT1 across multiple cancer types using integrated TCGA and GTEx datasets. Expression values are presented as log2(TPM+1). Red dots represent tumor samples and blue dots represent normal tissues. GBM samples are highlighted within the pan-cancer comparison. The right panels display direct comparisons between GBM tumor tissues and normal brain samples. Statistical significance between tumor and normal tissues is indicated by asterisks (*p < 0.05, **p < 0.01, ***p < 0.001). Sample numbers for tumor (T) and normal (N) groups are indicated below each plot.