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. 2002 Oct 26;325(7370):941. doi: 10.1136/bmj.325.7370.941

Table 4.

 Drugs prescribed for patients with angina before and after introduction of computerised decision support system. Values are numbers (percentages) of patients unless stated otherwise

Computerised system (n=1415)
Controls (n=1466)
Odds ratio (95% CI)
Short acting glyceryl trinitrate 813 (58); 806 (57) 831 (57); 802 (55) 1.11 (0.87 to 1.41)
β Blockers 666 (47); 683 (48) 712 (49); 718 (49) 0.99 (0.73 to 1.33)
Verapamil 21 (2); 24 (2) 18 (1); 21 (1) 1.02 (0.57 to 1.82)
Modified release glyceryl trinitrate 46 (3); 37 (3) 46 (3); 43 (3) 0.97 (0.50 to 1.54)
Transdermal glyceryl trinitrate 19 (1); 14 (1) 34 (2); 27 (2) 1.03 (0.54 to 1.98)
Isosorbide dinitrate (short acting and modified release) 64 (5); 56 (4) 86 (6); 79 (5) 0.91 (0.63 to 1.31)
Isosorbide mononitrate (short acting and modified release) 522 (37); 524 (37) 556 (38); 547 (37) 1.11 (0.79 to 1.56)
Diltiazem 270 (19); 269 (19) 310 (21); 287 (20) 1.43 (0.87 to 2.34)
Calcium channel blockers 396 (28); 380 (27) 377 (26); 368 (25) 1.12 (0.80 to 1.58)
Statins 409 (29); 498 (35) 435 (30); 550 (38) 0.92 (0.67 to 1.25)
β Blocker and dinitrate* 20 (1); 20 (1) 34 (2); 30 (2) 1.24 (0.66 to 2.33)
Calcium blocker and dinitrate* 22 (2); 24 (2) 41 (3); 37 (3) 1.15 (0.68 to 1.95)
Nitrate, calcium blocker, and β blocker* 113 (8); 102 (7) 115 (8); 120 (8) 0.75 (0.46 to 1.22)
*

Guideline specifically recommended not using these combinations.