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. 2026 Mar 18;16(3):e110131. doi: 10.1136/bmjopen-2025-110131

Table 1. Baseline characteristics of the study patients (n=3977).

No preoperative COVID-19
(n=766)
Preoperative COVID-19
(n=3211)
P value
Age (year), n (%) <0.001*
 <65 423 (55.2) 2235 (69.6)
 ≥65 343 (44.8) 976 (30.4)
BMI (kg/m2), median (IQR) 25.3 (22.9, 27.7) 24.9 (22.7, 27.3) 0.010*
Sex, n (%) 0.173†
 Male 362 (47.2) 1425 (44.4)
 Female 404 (52.8) 1786 (55.6)
Comorbidities, n (%)
 Diabetes 143 (18.7) 502 (15.6) 0.046†
 Hypertension 334 (43.6) 1174 (36.6) <0.001†
 Coronary artery disease 56 (7.3) 239 (8.3) 0.423†
 Stroke 21 (2.7) 48 (1.5) 0.026†
 Severe liver disease 4 (0.5) 20 (0.6) 0.949†
 Chronic kidney disease 3 (0.4) 15 (0.5) 1.000†
Smoke, n (%) 0.002†
 Never smoked 582 (76.0) 2623 (81.7)
 Formerly smoked 92 (12.0) 299 (9.3)
 Currently smoke 92 (12.0) 289 (9.0)
Vaccination against COVID-19, n (%) <0.001†
 0 94 (12.3) 306 (9.5)
 1–2 97 (12.7) 443 (13.9)
 ≥3 575 (75.1) 2459 (76.6)
ASA, n (%) 0.035†
 I 107 (14.0) 438 (13.7)
 II 578 (75.9) 2317 (72.4)
 III 75 (9.8) 422 (13.2)
 IV 2 (0.3) 23 (0.7)
Type of anaesthesia, n (%) <0.001†
 Regional anaesthesia 124 (16.2) 275 (8.6)
 General anaesthesia 642 (83.8) 2935 (91.4)
Duration of surgery (hour), median (IQR) 121.0 (89.0, 181.8) 120.0 (80.0, 179.0) 0.007*
Type of surgery, n (%) <0.001†
 Gynaecological surgery 61 (8.0) 393 (12.2)
 Orthopaedic surgery 492 (64.2) 1317 (41.0)
 Urological surgery 47 (6.1) 454 (14.1)
 General surgery 65 (8.5) 424 (13.2)
 Neurosurgery 34 (4.4) 211 (6.6)
 Cardiothoracic surgery 67 (8.7) 344 (10.7)

Values are n (%) unless otherwise indicated.

*

Mann-Whitney U test.

†χ

2 test.

ASA, American Society of Anesthesiologists classification; BMI, body mass index.