Figure 2:

Characterization of the Immune Landscape and Cell-Cell Communication in the Cervical Cancer TME. (A) UMAP visualization of immune cell populations. (B) Heatmap displaying the top 50 differentially expressed genes for each identified immune cell subset, see Table S1. (C) Pie chart showing the distribution of immune cell populations across individual patients, color coding according to the cell clusters in (A). (D) Violin plots of the proportion of each cell type; each dot represents an individual patient. (E-G) Cell-cell communication using CellChat: (E) Number of interactions visualized as circle plots (left) and as a heatmap (right), line width and color gradient indicate interaction count, respectively. (F) Interaction strength visualized similarly: circle plots (left) and heatmap (right), line width and color gradient indicate signaling strength, respectively. (G) Heatmap summarizing all outgoing and incoming signaling pathways for each cell type.