TABLE 2.
PCR for C. pneumoniae in the CSF of patients with clinically definite MS
Patient | Diagnosisa | Age (yr) | Gender | CSF characteristics
|
IgG indexb | OCc bands | PCR assay results
|
||||
---|---|---|---|---|---|---|---|---|---|---|---|
VUMCd
|
USF with MOMP primere | ||||||||||
Cell count (no. of cells/μl) | Protein concn (mg/dl) | Glucose concn (mg/dl) | VU-MOMP | Tong and Sillis | |||||||
1 | Sec MS | 45 | F | NDf | ND | ND | ND | ND | + | + | + |
2 | RR MS | 47 | M | 4 | 44 | 58 | 1.2 | + | + | − | + |
3 | RR MS | 26 | F | ND | ND | ND | ND | ND | + | + | + |
4 | RR MS | 40 | M | 1 | 34 | 68 | 0.6 | − | + | + | + |
5 | RR MS | 51 | M | 4 | 62 | 54 | 1.27 | + | + | + | + |
6 | RR MS | 59 | F | 2 | 51 | 60 | 0.6 | + | − | − | + |
7 | RR MS | 48 | F | 2 | 48 | 59 | 0.7 | + | + | − | + |
8 | Sec MS | 58 | M | 2 | 67 | 100 | 1.09 | − | + | + | + |
9 | Sec MS | 44 | F | 1 | 66 | 63 | 1.15 | + | + | + | + |
10 | Sec MS | 55 | M | 0 | 35 | 69 | 0.75 | + | − | − | − |
11 | Sec MS | 42 | F | 1 | 31 | 54 | 0.84 | + | − | + | − |
12 | RR MS | 55 | F | 1 | 28 | 48 | 0.73 | + | − | − | − |
13 | RR MS | 55 | F | 2 | 37 | 57 | 0.49 | − | + | + | − |
14 | Sec MS | 61 | F | ND | ND | ND | ND | ND | + | + | − |
15 | Sec MS | 66 | F | 1 | 64 | 61 | 0.58 | − | + | + | − |
16 | RR MS | 32 | F | 5 | 17 | 61 | 0.72 | − | − | − | − |
17 | Sec MS | 57 | M | 4 | 82 | 64 | 0.57 | + | + | + | + |
18 | RR MS | 62 | M | 3 | 43 | 55 | 0.07 | + | + | + | + |
Abbreviations: Sec MS, secondary progressive MS; RR MS, relapsing remitting MS.
IgG, immunoglobulin G.
OC, oligoclonal.
The total numbers of samples positive were 13 and 12 for the Vu-MOMP and Tong and Sillis primers, respectively.
The total number of samples positive was 11.
ND, not done.